Scientific Works

Actual Position:

Since 2020 – Project manager for Siric CARPEM.

Past Labs & Companies:

2017 – 2019: Centre de Recherche des Cordeliers – Project manager for HTE Program

2014 – 2017: Inception Sciences – Research Engineer

2011 – 2014: Inserm U1149 – Post Doc

2006 – 2011: Inserm U1162 – PhD Student

2005 – 2006: Inserm U889 (now U1053) – Bordeaux

Scientific Production:

1: Integrative Network-based Analysis of Colonic Detoxification Gene Expression in Ulcerative Colitis According to Smoking Status.  Ding YP, Ladeiro Y, Morilla I, Bouhnik Y, Marah A, Zaag H, Cazals-Hatem D, Seksik P, Daniel F, Hugot JP, Wainrib G, Tréton X, Ogier-Denis E. J Crohns Colitis. 2017 Apr 1;11(4):474-484. doi: 10.1093/ecco-jcc/jjw179. PubMed PMID: 27702825.


2: Integration of tumour and viral genomic characterizations in HBV-related hepatocellular carcinomas. Amaddeo G, Cao Q, Ladeiro Y, Imbeaud S, Nault JC, Jaoui D, Gaston Mathe Y, Laurent C, Laurent A, Bioulac-Sage P, Calderaro J, Zucman-Rossi J. Gut. 2015 May;64(5):820-9. doi: 10.1136/gutjnl-2013-306228. Epub 2014 Jun 9. PubMed PMID: 25021421; PubMed Central PMCID: PMC4392232.


3: Combined NADPH oxidase 1 and interleukin 10 deficiency induces chronic endoplasmic reticulum stress and causes ulcerative colitis-like disease in mice. Tréton X, Pedruzzi E, Guichard C, Ladeiro Y, Sedghi S, Vallée M, Fernandez N, Bruyère E, Woerther PL, Ducroc R, Montcuquet N, Freund JN, Van Seuningen I, Barreau F, Marah A, Hugot JP, Cazals-Hatem D, Bouhnik Y, Daniel F, Ogier-Denis E. PLoS One. 2014 Jul 9;9(7):e101669. doi: 10.1371/journal.pone.0101669. eCollection 2014. PubMed PMID: 25014110; PubMed Central PMCID: PMC4090121.


4: A functional screening identifies five microRNAs controlling glypican-3: role of miR-1271 down-regulation in hepatocellular carcinoma. Maurel M, Jalvy S, Ladeiro Y, Combe C, Vachet L, Sagliocco F, Bioulac-Sage P, Pitard V, Jacquemin-Sablon H, Zucman-Rossi J, Laloo B, Grosset CF. Hepatology. 2013 Jan;57(1):195-204. doi: 10.1002/hep.25994. PubMed PMID: 22865282.


5: Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma. Guichard C, Amaddeo G, Imbeaud S, Ladeiro Y, Pelletier L, Maad IB, Calderaro J, Bioulac-Sage P, Letexier M, Degos F, Clément B, Balabaud C, Chevet E, Laurent A, Couchy G, Letouzé E, Calvo F, Zucman-Rossi J. Nat Genet. 2012 May 6;44(6):694-8. doi: 10.1038/ng.2256. PubMed PMID: 22561517; PubMed Central PMCID: PMC3819251.


6: Effect of engineered nanoparticles on vasomotor responses in rat intrapulmonary artery. Courtois A, Andujar P, Ladeiro Y, Ducret T, Rogerieux F, Lacroix G, Baudrimont I, Guibert C, Roux E, Canal-Raffin M, Brochard P, Marano F, Marthan R, Muller B. Toxicol Appl Pharmacol. 2010 Jun 1;245(2):203-10. doi: 10.1016/j.taap.2010.03.002. Epub 2010 Mar 7. PubMed PMID: 20214918.


7: Identification of novel oncogenes and tumor suppressors in hepatocellular carcinoma. Imbeaud S, Ladeiro Y, Zucman-Rossi J. Semin Liver Dis. 2010 Feb;30(1):75-86. doi: 10.1055/s-0030-1247134. Epub 2010 Feb 19. Review. PubMed PMID: 20175035.


8: miRNAs in cancer: the case of liver tumors. Ladeiro Y, Zucman-Rossi J. Med Sci (Paris). 2009 May;25(5):467-72. doi: 10.1051/medsci/2009255467. Review. French. PubMed PMID: 19480827.


9: Impairment of NO-dependent relaxation in intralobar pulmonary arteries: comparison of urban particulate matter and manufactured nanoparticles. Courtois A, Andujar P, Ladeiro Y, Baudrimont I, Delannoy E, Leblais V, Begueret H, Galland MA, Brochard P, Marano F, Marthan R, Muller B. Environ Health Perspect. 2008 Oct;116(10):1294-9. doi: 10.1289/ehp.11021. Epub 2008 May 21. PubMed PMID: 18941568; PubMed Central PMCID: PMC2569085.


10: MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations. Ladeiro Y, Couchy G, Balabaud C, Bioulac-Sage P, Pelletier L, Rebouissou S, Zucman-Rossi J. Hepatology. 2008 Jun;47(6):1955-63. doi: 10.1002/hep.22256. PubMed PMID: 18433021.